Opioids, widely used in the treatment of acute and chronic pain, are sometimes limited by their numerous adverse effects, the most common being opioid-induced constipation (OIC), an often debilitating side effect of therapy. Bulk-forming laxatives (eg, psyllium, methylcellulose), which are considered safe in most cases of constipation, can be harmful to patients with OIC. These agents are not likely to relieve symptoms of OIC and may even be detrimental, as they are associated with abdominal pain and increase the risk for intestinal obstruction, and are generally not recommended. Compounding pharmacists are often called upon to prepare medications to either prevent or reverse OIC.

Indigestion, characterized by upper abdominal fullness and/or pain, heartburn, nausea, and belching, is frequently caused by gastroesophageal reflux disease (GERD) or gastritis. When antacids alone or other treatments fail, a "G.I. cocktail", a general term for a mixture of liquid antacid, viscous lidocaine, and an anticholinergic drug, may provide relief for indigestion.

Whether you are suffering from opioid-induced constipation or indigestion, or another gastrointestinal condition, your compounding pharmacist may be able to prepare medications unique to you and your needs and get you feeling better in no time.